Mikayla Woods, a starting guard from Pflugerville Hendrickson, led the Roadrunners with 12 points and 4 assists.
Adryana Quezada, a starting forward from Frisco Lone Star, had 11 points.
Charlene Mass, from Converse Veterans Memorial, came off the bench at guard and had 10 points.
Macy Ray led Incarnate Word with 10 points. Ray is a sophomore guard from Katy Taylor.
The Roadrunners (2-0) play their next game on the road Thursday against Texas. UTSA is back at home next Monday against University of the Southwest.
Incarnate Word (1-1) plays its next game at home on Nov. 19 against Texas A&M International.
